India is home to an estimated 2.3 million HIV patients

India is home to an estimated 2.3 million HIV patients of which 6 lakh would require to be on ART. At present, 3.55 lakh HIV patients are receiving first line treatment in 285 NACO ART centres.

Ten centres have rolled out second line ART to 1,701 HIV patients. Five more centres in Nagpur, Pune, Salem, Aurangabad and Surat have been trained to start second line ART while two centres in Vijayawada and Hubli are being prepared.

India rolled out second line ART for the first time on December 1, 2008 in Mumbai's J J Hospital and Chennai's Tambaram ART centre.

Resistance to first line treatment mainly happens because of poor adherence to the treatment regimen. If not put on second line immediately, most of these patients die within a few years.

A CD-4 count test is used to gauge immunity levels of an HIV-infected patient and to assess whether damage caused by the virus requires life-saving ART. The CD-4 count in healthy adults ranges from 500 to 1,500 cells per cubic millimetre of blood. In HIV infected people, it goes down by 60 cells per cubic millimetre of blood per year as HIV progresses. ART is administered when an HIV positive person registers a CD-4 count under 200.