New Clinical Signs of HIV in the Era of HAART Therapy

New Clinical Signs of HIV in the Era of HAART Therapy

The clinical spectrum of disease among people with HIV has changed dramatically in the era of HAART. NIAID and its grantees are actively studying the new clinical syndrome of disease among people on long- term therapy. Research is concentrating on the impact of HIV over the long term, the toxicity of the medicines used to control HIV, and the effects of aging on HIV disease progression. People with HIV have a variety of conditions including diabetes, heart disease, neurocognitive decline, and cancers that may, or may not, be directly due to HIV or its treatment. Long-term studies of people with HIV in the United States and abroad are underway.

NIAID Research on the Pathogenesis of AIDS

NIAID-supported scientists conduct research on HIV pathogenesis in laboratories on the campus of the National Institutes of Health (NIH) in Bethesda, Maryland; at the Institute's Rocky Mountain Laboratories in Hamilton, Montana; and at universities and medical centers in the United States and abroad.

An NIAID-supported resource, the NIH AIDS Research and Reference Reagent Program, in collaboration with the World Health Organization, provides critically needed AIDS-related research materials free to qualified researchers around the world.

The NIH Centers for AIDS Research, supported by NIAID in collaboration with six other NIH Institutes, fosters and facilitates development of infrastructure and interdisciplinary collaboration of HIV researchers at major medical and research centers across the United States.

In addition, the Institute convenes groups of investigators and advisory committees to exchange scientific information, clarify research priorities, and bring research needs and opportunities to the attention of the scientific community.