Tuesday, July 13, 2010

Fixed-dose combinations

Fixed-dose combinations

In addition, there are also several fixed-dose combination pills that combine two or more NRTIs with an NtRTI in a single tablet:

  • AZT + 3TC (Combivir): the two NRTIs zidovudine and lamivudine
  • AZT + 3TC + ABC (Trizivir): the NRTIs zidovudine, lamivudine and abacavir
  • 3TC + ABC (Kivexa /Epzicom): two NRTIs
  • FTC + TDF (Truvada): the NRTI emtricitabine with the NtRTI tenofovir

There is one fixed-dose combination pill combining all three types of reverse transcriptase inhibitors:

  • FTC + TDF + EFV (Atripla): one NRTI, one NtRTI, and the NNRTI efavirenz.

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